Critical Care Obstetrics and Gynecology

Eccrine Poroma in the Breast Mimicking Malignancy: A Case Report and Review of the Literature

Introduction: Eccrine Poroma (EP) is a rare benign adnexal neoplasm originating from the intra-epidermal portion of the sweat gland duct. The breast is an extremely rare site for this tumor, with only one reported case in the literature. This report highlights its unusual clinical presentation, surgical approach and follow-up.

Objective: Aim of this study is to present a case report of EP involving the breast and to review the existing literature on this rare cutaneous neoplasm in atypical anatomical locations.

Materials and methods: A 66-year-old woman presented with a slow-growing cutaneous lesion on her left breast. Clinical examination revealed a pink bluish dome-shaped nodule. Imaging studies was suggestive of breast tumor with low suspicion of malignancy. Histopathological examination and immunohistochemical staining confirm the diagnostic of eccrine poroma. Surgical excision with clear margins was performed and no recurrence or malignant transformation was observed.

Results: Eccrine poroma of the breast is a rare benign tumor that can present diagnostic challenges, particularly when they mimic malignant lesions clinically and radiologically. Histopathological examination remains the gold standard for diagnosis, immunohistochemical staining can further support the diagnosis. Treatment typically involves surgical excision with clear margins and prognosis is excellent, with low rates of recurrence or malignant transformation.

Conclusion: EP is known as the great imitator due to its clinical and dermoscopic diversity. Despite its rare occurrence, EP should be considered in the differential diagnosis of a slowly growing breast mass with typical clinical features.

Author(s): Amal Benchine1, Najwa Loukili1, Samia Sassi2, El Hassouni Fatima1, Mouniya El Youssfi1 and Samir Bargach1

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