Critical Care Obstetrics and Gynecology

The Role of Stem Cells of the Basal Layer of Endometrium in Gynaecological Diseases

Stem cells of the endometrium belong to epithelial and stromal cells, capable of self-reproduction in vitro. Epithelial cells differentiate into cytokeratin-positive iron-like structures, and stromal cells are multipotent and can differentiate into adipocytes, chondrocytes and osteoblasts. Epithelial progenitor and mesenchymal stem cells have a regenerative ability to restore the endometrium during the menstrual cycle. These cells can participate in the development of diseases such as endometriosis, adenomyosis, endometrial hyperplasia, endometrial cancer, and also provide a resource for cell therapy.

Author(s):

Bayramova AN

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