Critical Care Obstetrics and Gynecology

SARS-CoV-2 During Pregnancy and Associated Cytokine-Storm.

Coronavirus disease 2019 (SARS-CoV-2) is an emerging pandemic disease. Coronaviruses cause illness spectrums changing from the common cold to serious respiratory illness and death. Available data about coronavirus disease 2019 during pregnancy are limited because of the limited studies. However, no vertical transmission maternal to fetal is proven in recent studies. Pregnancy complicated with Coronavirus can cause spontaneous abortion, miscarriages, preterm deliveries, intrauterine growth restriction, and fetal demise. Pregnancy complicated with Coronavirus can be due to severe acute respiratory syndrome, disseminated intravascular coagulopathy, renal failure, secondary bacterial pneumonia, and sepsis. And also maternal infection during pregnancy contribute elevated cytokines leading to cytokine-storm. Cytokine-storm-related Coronavirus 19 infection at pregnancy can deteriorate fetal development. Fetal neuronal dysfunction, atypical behavioural phenotypes, autism, and attention-deficits are related to viral infections at the time of pregnancy.

Author(s):

Uysal Çetin Gülçin

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