Modalities for termination of pregnancy may result in some adverse effects especially uterine rupture in women with the previous cesarean section. Here we report uterine rupture in the 23rd week of pregnancy after Misoprostol uses for abortion induction in second pregnancy with the previous cesarean section. The rupture was repaired via laparotomy. Totally, our results demonstrated that further cautions should be provided in women presenting for abortion in second pregnancy trimester especially in previous cesarean section and with dose adjustments and some other strategies to attain higher safety in this era and for reduction of possible uterine ruptures.
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